NAD+ 1000mg
£57.99 per vial · Coenzymes · Research use only
About NAD+ 1000mg
NAD+ 1000mg is nicotinamide adenine dinucleotide, a coenzyme research material, supplied as lyophilised powder in a single vial for in-vitro laboratory research.
Product specifications
- Compound
- NAD+
- Declared content
- 1000mg per vial
- Format
- Lyophilised powder
Batch documentation
The current published lot is IP-NAD1000-001. The batch record from Janoshik Analytical (CZ), dated 18 March 2026, lists measured content of 1072 mg/vial.
View the certificate of analysis →
Intended use
For in-vitro laboratory research only. Not for human or veterinary use.
Technical notes and further reading
- CAS number
- 53-84-9
- Molecular formula
- C21H27N7O14P2
- Molecular weight
- 663.4 g/mol
Specification
| SKU | NJ1000 |
|---|---|
| Compound | NAD+ |
| Price | £57.99 per vial |
| Format | 1000mg per vial |
| Availability | In stock |
| CAS number | 53-84-9 |
| Molecular formula | C21H27N7O14P2 |
| Molecular weight | 663.4 g/mol |
| Published batch / lot | IP-NAD1000-001 |
| Reported purity | See the material's batch documentation |
| Measured content | 1072 mg/vial |
| Identity status | LC-MS identity result not published |
| Tested by | Janoshik Analytical (CZ) |
| Report date | 2026-03-18 |
| Storage | Lyophilised: −20 °C, protect from light |
| Intended use | In-vitro laboratory research only |
What does the research on NAD+ investigate?
The one gram fill of NAD+ is the largest quantity by weight of any single material in this catalogue, and the reason is simply that the molecule is small: at 663.4 g/mol, a gram is about one and a half millimoles. That is a very different proposition to a milligram of a five kilodalton peptide, and it means this listing suits work where the coenzyme is consumed in quantity rather than used sparingly. The chemistry that makes it worth having in bulk is that it is the central electron carrier in a large family of redox reactions, cycling between an oxidised and a reduced form. Both states are relevant to any measurement, they are distinguishable spectrophotometrically, and the ratio between them changes on storage as the molecule hydrolyses and oxidises. Nothing here describes a use, benefit, dose or effect in people.
Is NAD+ legal in the UK?
NAD+ is not a licensed medicine in the United Kingdom and is not listed in any schedule of the Misuse of Drugs Act 1971. Selling it as a research chemical is a lawful trade; what the law restricts is the purpose it is sold for, not the fact that it is sold.
Three pieces of legislation frame that distinction. The Human Medicines Regulations 2012 make it an offence to sell an unlicensed product for human use. The Psychoactive Substances Act 2016 prohibits supplying a psychoactive substance for human consumption, which is why a research-only basis is not a formality. The Misuse of Drugs Act 1971 would apply only if the compound were scheduled, and it is not. Each of these turns on the purpose of the supply, so the statements on this page are written plainly rather than tucked into small print.
In practice that means a supplier may lawfully sell to a researcher, research organisation or business buying for research, and the buyer confirms at checkout that they are 18 or over, buying in the course of research, and responsible for handling, storing and disposing of the material lawfully. Nothing here is legal advice for your own circumstances; if you need a position, take qualified advice.
NAD+ is not licensed as a medicine in the United Kingdom in the form supplied here.
How are identity and quality assured?
Each released lot is tested and the result is published, rather than the material being described as high purity on the strength of a supplier's word. Purity is measured by reversed-phase HPLC at an independent laboratory. The laboratory used for every lot published so far is Janoshik Analytical, in the Czech Republic, and the result is stated alongside the measured content against label so the two can be read together.
The report carries the lot number printed on the vial, which is the part that matters. A certificate showing a result without a lot number cannot be tied to the vial in front of you, and a certificate for a different lot tells you nothing about yours. Matching the printed number on the label to the number on the report is a five second check and it is the whole point of publishing both.
Identity confirmation by mass spectrometry is a separate test and is ordered as an add-on, so the figures published here come from RP-HPLC purity testing unless a report says otherwise. Where no report is published for a listing yet, the documentation held for the lot being shipped can be requested before you order. We would rather send you what exists than let you assume a certificate is available when it is not.
Synthesis and supply
Peptide material is built by solid-phase synthesis, purified by preparative HPLC, then lyophilised. Lyophilisation freezes the solution and removes the solvent under vacuum, which is why the vial arrives holding a cake or powder rather than a liquid and why a solvent has to be added before the material can be worked with. Removing water also removes the main route by which a peptide degrades in storage, which is the reason the format is used.
Sequence length and modification are what make batches differ in difficulty. Every coupling step is an opportunity for a truncated or deleted by-product, and a heavily modified or long chain presents more of them, which is why the purity trace rather than the headline figure is what a certificate is read for. Vials are filled and labelled with the lot number, and the lot number is what the report and the verification lookup resolve against.
Materials supplied in gram quantities are usually produced by fermentation or enzymatic conversion rather than stepwise chemical synthesis, and the trace impurities that accompany them come from that route rather than from incomplete couplings.
External resources for researchers
These are the public reference sources we use when checking the identity of NAD+, and the ones worth going to before relying on anything stated on a product page, including this one.
- PubChem — Compound records, computed properties, depositor-supplied identity data.
- CAS Common Chemistry — CAS Registry lookups where a registry number is known.
- ChEBI — Curated chemical ontology entries with cross-references.
- Europe PMC — Primary literature search by compound name, sequence or registry number.
- Certificate hub — Reports published for the lots released so far.
Frequently asked questions
What does the salvage route refer to?
NAD+ that is consumed rather than regenerated — cleaved at the nicotinamide–ribose bond by transferase and deacylase enzymes — is rebuilt from nicotinamide by a short enzymatic route instead of being made from tryptophan each time. It is standard background for anyone working with NAD-consuming enzymes in vitro.
How is a large fill best handled once opened?
Let the vial reach room temperature before breaking the seal, so that atmospheric moisture does not condense onto a cold hygroscopic solid. For a fill that will be sampled repeatedly, weighing out sub-portions into separate sealed containers at first opening avoids exposing the whole gram every time.
Is this the same substance as NMN or nicotinamide riboside?
No. Those are biosynthetic precursors with their own CAS numbers and much lower molecular masses. NAD+ under CAS 53-84-9 is the intact dinucleotide at 663.4 g/mol, and the three are not interchangeable in an assay that requires the cofactor itself.
Is NAD+ supplied for human or veterinary use?
No. Every product on this site is supplied strictly for in-vitro laboratory research. NAD+ is supplied as a lyophilised powder in a sealed vial and is not a medicine, supplement, food, cosmetic or veterinary product. It is not supplied for human or animal consumption, administration, or any in-vivo use, and no dose, route or human application is described or offered anywhere on this page. Buyers confirm they are 18 or over and purchasing in the course of research.
How is the purity figure measured, and what does it actually tell me?
Purity is measured by reversed-phase HPLC at an independent laboratory, and the result is published with the method conditions rather than as a bare percentage. The figure is the proportion of the UV-absorbing material in the chromatogram that elutes as the target peak. It describes the sample as analysed; it is not a statement about what the material is for. A high figure alongside a clean chromatogram is the useful combination, which is why the report is worth reading rather than the headline number alone.
What documentation comes with a batch?
Each released lot carries a number printed on the vial label and a report stating purity by RP-HPLC, measured content against label, and the testing laboratory. Reports published so far are listed on this page and collected on the certificate hub, and each carries a lot number that can be checked against the vial in front of you. Where a report is not yet published for a listing, ask before ordering and we will send the documentation that exists for the lot being shipped.
How should NAD+ be stored?
In the form supplied, as a lyophilised powder, the material is stable kept cold, dry and dark. For powder, that means a freezer at around minus 20 degrees Celsius, desiccated, with the vial sealed and shielded from light, which is how it should stay until you are ready to work with it. Bringing a vial to room temperature before opening avoids condensation on the contents. Once in solution the material is less stable than the powder and should be kept cold and used within a short working window. Choosing a solvent and a storage regime for your own work is your call, not ours.
Do I need bacteriostatic water to prepare it?
A lyophilised powder needs a solvent added before it can be worked with. Bacteriostatic water, which is water with 0.9% benzyl alcohol, is the common choice because the preservative extends the working life of the solution once the vial has been opened, and we supply it in 3ml and 10ml vials. It is not the only option: where a method cannot tolerate benzyl alcohol, use the solvent the method specifies. The choice affects the sample, so it belongs to the researcher.
How and when is an order shipped?
Orders are dispatched from the United Kingdom. An order placed before 4pm on a working day is collected the same day; weekends and bank holidays roll forward to the next working day. Delivery is tracked, and shipping is free on UK orders over 30 pounds, with tracked 48 hour service at 3.65 pounds below that. Tracking is sent when the parcel is collected, so the first scan is usually visible the same evening.
How much material is one gram of NAD+?
About one and a half millimoles at a molecular weight of 663.4 g/mol. Comparing that to the other listings here is instructive: a milligram of a five kilodalton peptide and a milligram of NAD+ differ by roughly a factor of eight in molar terms, and the fills differ by a further factor of a thousand. Read the label in moles before assuming the scale of what is in the vial.
What is the most likely change on storage?
Hydrolysis at the pyrophosphate linkage and conversion between the oxidised and reduced states. The first produces smaller nucleotide fragments, which is degradation in the ordinary sense. The second does not destroy the molecule but changes which species is present, and it matters because every assay that uses this coenzyme depends on which state it starts in. Keeping the material cold and dry slows both.
Why does the fill weight need interpreting carefully?
Because the material is hygroscopic and absorbs water from the atmosphere. A weight-based fill check therefore measures the material plus whatever moisture it has taken up, and the two are not separable by weighing alone. This is a property of the compound rather than a shortcoming of any particular batch, and it is why sealed storage and letting the vial reach room temperature before opening both matter.
What should be requested for a batch of this size?
Documentation that distinguishes the two redox states and reports the water content, alongside the usual identity and purity results. For a gram-scale fill the consequences of a wrong assumption propagate through far more work than for a milligram vial, so it is worth being specific about what the certificate does and does not establish before committing to it.
Documentation & batch verification
The current released lot is IP-NAD1000-001, tested 2026-03-18 by Janoshik Analytical (CZ): measured content 1072 mg/vial, identity Purity confirmed (RP-HPLC). The full report for this lot is published and can be checked online — verify this batch. See the full record for lot IP-NAD1000-001 or all published certificates of analysis.
Published batch records show the laboratory, report date, purity and measured content where reported. Check the certificate for the exact lot: an HPLC purity result does not establish LC-MS identity, sterility or suitability for human or animal use. Review the published batch record before ordering.
Order NAD+ 1000mg online — UK dispatch · Request an invoice · Verify a batch
Research use only. Not for human or animal consumption.