NAD+ — Compound Overview
A researcher-focused overview of NAD+: the coenzyme's chemistry, its role in the research literature, and how each batch is documented.
Last updated: 2026-08-21 · By: Index Peptides technical team
Key facts about NAD+
| Compound | NAD+ |
|---|---|
| CAS number | 53-84-9 |
| Molecular formula | C21H27N7O14P2 |
| Molecular weight | 663.4 g/mol |
| Listed formats | 500mg per vial, 1000mg per vial |
| Intended use | In-vitro laboratory research only |
What is NAD+?
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in every living cell. It consists of two nucleotides — one carrying an adenine base, the other nicotinamide — joined through their phosphate groups. Unlike the synthetic peptides in the catalogue, NAD+ is a naturally ubiquitous small molecule; the research material supplied is the purified, lyophilised compound.
Chemistry and structure
NAD+ carries CAS registry number 53-84-9, molecular formula C21H27N7O14P2 and a molecular weight of approximately 663.4 g/mol. The molecule exists in oxidised (NAD+) and reduced (NADH) forms, and this redox couple is the basis of its biochemical role as an electron carrier.
NAD+ in the research literature
NAD+ is one of the most-studied molecules in biochemistry. It functions as an electron carrier in central energy metabolism (glycolysis, the citric-acid cycle, oxidative phosphorylation) and as a substrate for NAD-consuming enzyme families including sirtuins and PARPs. It is a standard reagent in enzymology, metabolism and cell-biology research.
Regulatory status
The NAD+ supplied by Index Peptides is laboratory reagent material for in-vitro research. It is not a medicine, supplement or food ingredient as supplied, and it is not for human or veterinary use.
Form, handling and storage
Supplied as a lyophilised powder in a sealed vial. NAD+ is hygroscopic and degrades in solution, particularly at alkaline pH and elevated temperature — store the powder at -20°C, desiccated and protected from light, per the batch record.
Batch documentation at Index Peptides
Review the published certificate for the exact lot, including the laboratory, report date and analytical results actually reported. HPLC purity alone does not confirm LC-MS identity. Contact us before ordering if a required result is not published.
Frequently asked questions
Is this the same NAD+ found in supplements?
Chemically NAD+ is NAD+, but the material here is supplied as a laboratory reagent for in-vitro research — not as a food, supplement or medicine, and not for human or animal use.
Why are there 500mg and 1000mg formats?
They are simply different vial quantities of the same documented material, for laboratories with different reagent requirements.
How should NAD+ be stored?
As lyophilised powder at -20°C, desiccated and protected from light. NAD+ is unstable in solution, so solutions should be prepared fresh per the experimental protocol.
How do I reconstitute NAD+?
Reconstitution is a laboratory handling procedure, not a use instruction. Our documentation-led reconstitution guide covers the mechanics of dissolving lyophilised peptide powders: https://indexpeptides.uk/guides/peptide-reconstitution-guide. Handling is the responsibility of the qualified researcher.
What is the shelf life of NAD+?
As supplied (lyophilised powder in a sealed vial), NAD+ is stored at -20C, desiccated and protected from light. Long-term stability is documented per batch on the certificate of analysis; treat the batch record as the authoritative shelf-life reference for that lot.
What is the difference between the sizes?
The difference is the nominal peptide content per vial. NAD+ is supplied as 500mg and 1000mg vials. Every format carries the same batch documentation and purity testing.
What does the certificate of analysis show?
Review the published certificate for the exact lot, including the laboratory, report date and analytical results actually reported. HPLC purity alone does not confirm LC-MS identity. Contact us before ordering if a required result is not published.
References
Research use only. Not for human or animal consumption.