SS-31 10mg
£27.99 per vial · Peptides · Research use only
About SS-31 10mg
SS-31 10mg is a synthetic peptide research material, supplied as lyophilised powder in a single vial for in-vitro laboratory research.
Product specifications
- Compound
- SS-31
- Declared content
- 10mg per vial
- Format
- Lyophilised powder
Batch documentation
The current published lot is SS100-0401. The batch record from Janoshik Analytical (CZ), dated 24 August 2026, lists reported purity of 99.873% (RP-HPLC) and measured content of 10.65 mg/vial.
View the certificate of analysis →
Intended use
For in-vitro laboratory research only. Not for human or veterinary use.
Technical notes and further reading
- CAS number
- 736992-21-5
- Molecular formula
- C32H49N9O5
- Molecular weight
- 639.8 g/mol
- Sequence
- D-Arg-Dmt-Lys-Phe-NH₂
Specification
| SKU | SS31 |
|---|---|
| Compound | SS-31 |
| Price | £27.99 per vial |
| Format | 10mg per vial |
| Availability | In stock |
| CAS number | 736992-21-5 |
| Molecular formula | C32H49N9O5 |
| Molecular weight | 639.8 g/mol |
| Sequence | D-Arg-Dmt-Lys-Phe-NH₂ |
| Published batch / lot | SS100-0401 |
| Reported purity | 99.873% (RP-HPLC) |
| Measured content | 10.65 mg/vial |
| Identity status | LC-MS identity result not published |
| Tested by | Janoshik Analytical (CZ) |
| Report date | 2026-08-24 |
| Storage | Lyophilised: −20 °C, protect from light |
| Certificate of analysis | Published for lot SS100-0401 — download it from this page, or request a copy |
| Intended use | In-vitro laboratory research only |
SS-31 10mg research peptide: UK product information
This SS-31 listing, also written SS31, contains 10mg of lyophilised research material per vial. Use both the compound name and vial quantity when comparing UK suppliers, and review the available lot documentation before purchase. The listed price is per vial; check current availability and the dispatch notice separately. Supplied for in-vitro laboratory research only.
What does the research on SS-31 investigate?
SS-31, also known as elamipretide, is a tetrapeptide of only four residues, and every one of them is there for a reason. It contains a D-arginine rather than the natural L form, a dimethyltyrosine, a lysine and a phenylalanine, with an amide at the C-terminal end. The result is a molecule that proteases handle poorly - the unnatural stereochemistry gives them little to recognise - and that carries a permanent positive charge, which is the property most of the research literature focuses on because it drives association with the inner mitochondrial membrane. That association, with a lipid called cardiolipin, is the subject of the in-vitro work. Analytically, chirality is the distinctive issue: a four-residue chain is small enough that the difference between the correct stereochemistry and the wrong one is a substantial fraction of the molecule, so chiral purity is a real question rather than a theoretical one. This page describes the material and its documentation only.
Who can buy SS-31?
SS-31 is supplied strictly as a research chemical for in-vitro laboratory research. Products are sold exclusively to qualified researchers and licensed laboratories.
At checkout the buyer confirms that they are 18 or over, are buying in the course of research, and are responsible for handling, storing and disposing of the material in line with their laboratory's procedures. SS-31 is not for human or veterinary use.
We only answer questions about specifications, documentation and orders.
How are identity and quality assured?
Each released lot is tested and the result is published, rather than the material being described as high purity on the strength of a supplier's word. Purity is measured by reversed-phase HPLC at an independent laboratory. The laboratory used for every lot published so far is Janoshik Analytical, in the Czech Republic, and the result is stated alongside the measured content against label so the two can be read together.
The report carries the lot number printed on the vial, which is the part that matters. A certificate showing a result without a lot number cannot be tied to the vial in front of you, and a certificate for a different lot tells you nothing about yours. Matching the printed number on the label to the number on the report is a five second check and it is the whole point of publishing both.
Identity confirmation by mass spectrometry is a separate test and is ordered as an add-on, so the figures published here come from RP-HPLC purity testing unless a report says otherwise. Where no report is published for a listing yet, the documentation held for the lot being shipped can be requested before you order. We would rather send you what exists than let you assume a certificate is available when it is not.
Synthesis and supply
Peptide material is built by solid-phase synthesis, purified by preparative HPLC, then lyophilised. Lyophilisation freezes the solution and removes the solvent under vacuum, which is why the vial arrives holding a cake or powder rather than a liquid and why a solvent has to be added before the material can be worked with. Removing water also removes the main route by which a peptide degrades in storage, which is the reason the format is used.
Sequence length and modification are what make batches differ in difficulty. Every coupling step is an opportunity for a truncated or deleted by-product, and a heavily modified or long chain presents more of them, which is why the purity trace rather than the headline figure is what a certificate is read for. Vials are filled and labelled with the lot number, and the lot number is what the report and the verification lookup resolve against.
Because the chain contains D-configured and non-natural residues, standard amino-acid analysis of the hydrolysate will not distinguish correct material from its stereoisomers, which is a genuine limitation of routine batch testing for this compound.
External resources for researchers
These are the public reference sources we use when checking the identity of SS-31, and the ones worth going to before relying on anything stated on a product page, including this one.
- PubChem — Compound records, computed properties, depositor-supplied identity data.
- CAS Common Chemistry — CAS Registry lookups where a registry number is known.
- ChEBI — Curated chemical ontology entries with cross-references.
- Europe PMC — Primary literature search by compound name, sequence or registry number.
- Certificate hub — Reports published for the lots released so far.
Frequently asked questions
Is SS-31 supplied for human or veterinary use?
No. SS-31 is supplied as a lyophilised powder in a sealed vial and is supplied strictly as a research chemical for in-vitro laboratory research. Products are sold exclusively to qualified researchers and licensed laboratories, and buyers confirm they are 18 or over and purchasing in the course of research. We only answer questions about specifications, documentation and orders.
How is the purity figure measured, and what does it actually tell me?
Purity is measured by reversed-phase HPLC at an independent laboratory, and the result is published with the method conditions rather than as a bare percentage. The figure is the proportion of the UV-absorbing material in the chromatogram that elutes as the target peak. It describes the sample as analysed; it is not a statement about what the material is for. A high figure alongside a clean chromatogram is the useful combination, which is why the report is worth reading rather than the headline number alone.
What documentation comes with a batch?
Each released lot carries a number printed on the vial label and a report stating purity by RP-HPLC, measured content against label, and the testing laboratory. Reports published so far are listed on this page and collected on the certificate hub, and each carries a lot number that can be checked against the vial in front of you. Where a report is not yet published for a listing, ask before ordering and we will send the documentation that exists for the lot being shipped.
How should SS-31 be stored?
In the form supplied, as a lyophilised powder, the material is stable kept cold, dry and dark. For powder, that means a freezer at around minus 20 degrees Celsius, desiccated, with the vial sealed and shielded from light, which is how it should stay until you are ready to work with it. Bringing a vial to room temperature before opening avoids condensation on the contents. Once in solution the material is less stable than the powder and should be kept cold and used within a short working window. Choosing a solvent and storage conditions for your own work is your call, not ours.
Do I need bacteriostatic water to prepare it?
A lyophilised powder needs a solvent added before it can be worked with. Bacteriostatic water, which is water with 0.9% benzyl alcohol, is the common choice because the preservative extends the working life of the solution once the vial has been opened, and we supply it in 3ml and 10ml vials. It is not the only option: where a method cannot tolerate benzyl alcohol, use the solvent the method specifies. The choice affects the sample, so it belongs to the researcher.
How and when is an order shipped?
Orders are dispatched from the United Kingdom. An order placed before 4pm on a working day is collected the same day; weekends and bank holidays roll forward to the next working day. UK orders go by tracked DPD next-day delivery, free on orders over 14 pounds and 4.99 pounds below that. Tracking is sent when the parcel is collected, so the first scan is usually visible the same evening.
What is unusual about the residues in SS-31?
Three things. The arginine is in the D configuration rather than the natural L form, one residue is dimethyltyrosine rather than ordinary tyrosine, and the chain terminates in an amide rather than a free acid. Together those features make the peptide resistant to the proteases that would otherwise dismantle a four-residue chain almost immediately. They also mean this is not a sequence that occurs naturally, so there is no parent peptide to compare it against.
What does the research literature focus on?
Association with cardiolipin, a phospholipid found on the inner mitochondrial membrane. The peptide carries a permanent positive charge and the published work describes it partitioning into the membrane in a way that depends on that charge. That is a described physicochemical interaction studied in model membrane systems and isolated mitochondrial preparations.
Why does chirality matter for this compound specifically?
Because the molecule is small. In a four-residue chain each residue is roughly a quarter of the total mass and structure, so getting the stereochemistry wrong is a large change rather than a subtle one - the wrong enantiomer will have different retention behaviour and different biological interactions. Routine testing that confirms mass and purity by HPLC will not by itself prove the stereochemistry is correct, and it is worth knowing that limit when reading a certificate.
How does the unnatural residues affect storage and handling?
Favourably. The features that make the peptide resistant to enzymatic breakdown also make it robust under ordinary handling, and there are no methionine or cysteine residues to oxidise. The practical requirement is the standard one for lyophilised material: keep it cold, dry and dark, and bring the vial to room temperature before opening so condensation does not collect on the powder.
What is dimethyltyrosine, and why is it in the chain?
It is a non-natural analogue of tyrosine carrying two additional methyl groups on its aromatic ring. Its presence is a deliberate design choice: the added methyls occupy the position that would otherwise be attacked first in an oxidising environment, so the residue resists a modification that would alter the molecule's mass and behaviour. Like the D-configured arginine, it is a stability feature rather than a change to how the peptide interacts with a membrane.
Does the permanent positive charge affect how it dissolves?
Favourably. A chain carrying a permanent positive charge is readily water-soluble, so the material goes into aqueous solution without an organic co-solvent, and there are no methionine or cysteine residues to oxidise. The same charge underlies the association with cardiolipin described in the literature, so it is a property worth knowing in both the handling and the reading.
Documentation & batch verification
The current released lot is SS100-0401, tested 2026-08-24 by Janoshik Analytical (CZ): RP-HPLC purity 99.873% (RP-HPLC), measured content 10.65 mg/vial, identity Purity confirmed (RP-HPLC). The full report for this lot is published and can be checked online — verify this batch. See the full record for lot SS100-0401 or all published certificates of analysis.
Published batch records show the laboratory, report date, purity and measured content where reported. Check the certificate for the exact lot: an HPLC purity result does not establish LC-MS identity, sterility or suitability for human or animal use. Review the published batch record before ordering.
Order SS-31 10mg online — UK dispatch · Request an invoice · Verify a batch
Research use only. Not for human or animal consumption.