Semax 5mg
£19.99 per vial · Peptides · Research use only
About Semax 5mg
Semax 5mg is a synthetic peptide research material, supplied as lyophilised powder in a single vial for in-vitro laboratory research.
Product specifications
- Compound
- Semax
- Declared content
- 5mg per vial
- Format
- Lyophilised powder
Batch documentation
The current published lot is IP-SEMAX-5-001. The batch record from Janoshik Analytical (CZ), dated 24 August 2026, lists reported purity of 99.282% (RP-HPLC) and measured content of 5.68 mg/vial.
View the certificate of analysis →
Intended use
For in-vitro laboratory research only. Not for human or veterinary use.
Technical notes and further reading
- CAS number
- 80714-61-0
- Molecular formula
- C37H51N9O10S
- Molecular weight
- 813.9 g/mol
- Sequence
- MEHFPGP (ACTH(4–10) analogue)
Specification
| SKU | SX5 |
|---|---|
| Compound | Semax |
| Price | £19.99 per vial |
| Format | 5mg per vial |
| Availability | In stock |
| CAS number | 80714-61-0 |
| Molecular formula | C37H51N9O10S |
| Molecular weight | 813.9 g/mol |
| Sequence | MEHFPGP (ACTH(4–10) analogue) |
| Published batch / lot | IP-SEMAX-5-001 |
| Reported purity | 99.282% (RP-HPLC) |
| Measured content | 5.68 mg/vial |
| Identity status | LC-MS identity result not published |
| Tested by | Janoshik Analytical (CZ) |
| Report date | 2026-08-24 |
| Storage | Lyophilised: −20 °C, protect from light |
| Certificate of analysis | Published for lot IP-SEMAX-5-001 — download it from this page, or request a copy |
| Intended use | In-vitro laboratory research only |
Semax 5mg: UK research material and documentation
This Semax listing contains 5mg of lyophilised material in a research vial. Selank is a separate product and its batch record cannot document a Semax purchase. Check the name, labelled quantity and lot on the available report when comparing UK laboratory suppliers. Review the current price and dispatch notice before ordering this in-vitro research material.
- Selank 5mg — Compare the current price, availability and batch record.
What does the research on Semax investigate?
Semax is a synthetic seven-residue peptide built from the ACTH(4-10) core with a proline-glycine-proline tail added at the C-terminal end. The design is a study in stability rather than in receptor activity: the short core sequence would be degraded quickly on its own, and the tripeptide tail is what makes the chain resistant to the peptidases that would otherwise take it apart. That makes it a useful model for anyone interested in how a small modification changes the lifetime of a peptide in a biological sample, which is where most of the in-vitro work sits. Analytically it is uncomplicated - a short, unmodified chain apart from the tail - with one clear liability: the N-terminal methionine is susceptible to oxidation, and an oxidised batch differs from an intact one by sixteen daltons on the methionine residue. Handling that avoids oxidising conditions is the practical concern. This page describes the material and its documentation only.
Who can buy Semax?
Semax is supplied strictly as a research chemical for in-vitro laboratory research. Products are sold exclusively to qualified researchers and licensed laboratories.
At checkout the buyer confirms that they are 18 or over, are buying in the course of research, and are responsible for handling, storing and disposing of the material in line with their laboratory's procedures. Semax is not for human or veterinary use.
We only answer questions about specifications, documentation and orders.
How are identity and quality assured?
Each released lot is tested and the result is published, rather than the material being described as high purity on the strength of a supplier's word. Purity is measured by reversed-phase HPLC at an independent laboratory. The laboratory used for every lot published so far is Janoshik Analytical, in the Czech Republic, and the result is stated alongside the measured content against label so the two can be read together.
The report carries the lot number printed on the vial, which is the part that matters. A certificate showing a result without a lot number cannot be tied to the vial in front of you, and a certificate for a different lot tells you nothing about yours. Matching the printed number on the label to the number on the report is a five second check and it is the whole point of publishing both.
Identity confirmation by mass spectrometry is a separate test and is ordered as an add-on, so the figures published here come from RP-HPLC purity testing unless a report says otherwise. Where no report is published for a listing yet, the documentation held for the lot being shipped can be requested before you order. We would rather send you what exists than let you assume a certificate is available when it is not.
Synthesis and supply
Peptide material is built by solid-phase synthesis, purified by preparative HPLC, then lyophilised. Lyophilisation freezes the solution and removes the solvent under vacuum, which is why the vial arrives holding a cake or powder rather than a liquid and why a solvent has to be added before the material can be worked with. Removing water also removes the main route by which a peptide degrades in storage, which is the reason the format is used.
Sequence length and modification are what make batches differ in difficulty. Every coupling step is an opportunity for a truncated or deleted by-product, and a heavily modified or long chain presents more of them, which is why the purity trace rather than the headline figure is what a certificate is read for. Vials are filled and labelled with the lot number, and the lot number is what the report and the verification lookup resolve against.
External resources for researchers
These are the public reference sources we use when checking the identity of Semax, and the ones worth going to before relying on anything stated on a product page, including this one.
- PubChem — Compound records, computed properties, depositor-supplied identity data.
- CAS Common Chemistry — CAS Registry lookups where a registry number is known.
- ChEBI — Curated chemical ontology entries with cross-references.
- Europe PMC — Primary literature search by compound name, sequence or registry number.
- Certificate hub — Reports published for the lots released so far.
Frequently asked questions
Is Semax supplied for human or veterinary use?
No. Semax is supplied as a lyophilised powder in a sealed vial and is supplied strictly as a research chemical for in-vitro laboratory research. Products are sold exclusively to qualified researchers and licensed laboratories, and buyers confirm they are 18 or over and purchasing in the course of research. We only answer questions about specifications, documentation and orders.
How is the purity figure measured, and what does it actually tell me?
Purity is measured by reversed-phase HPLC at an independent laboratory, and the result is published with the method conditions rather than as a bare percentage. The figure is the proportion of the UV-absorbing material in the chromatogram that elutes as the target peak. It describes the sample as analysed; it is not a statement about what the material is for. A high figure alongside a clean chromatogram is the useful combination, which is why the report is worth reading rather than the headline number alone.
What documentation comes with a batch?
Each released lot carries a number printed on the vial label and a report stating purity by RP-HPLC, measured content against label, and the testing laboratory. Reports published so far are listed on this page and collected on the certificate hub, and each carries a lot number that can be checked against the vial in front of you. Where a report is not yet published for a listing, ask before ordering and we will send the documentation that exists for the lot being shipped.
How should Semax be stored?
In the form supplied, as a lyophilised powder, the material is stable kept cold, dry and dark. For powder, that means a freezer at around minus 20 degrees Celsius, desiccated, with the vial sealed and shielded from light, which is how it should stay until you are ready to work with it. Bringing a vial to room temperature before opening avoids condensation on the contents. Once in solution the material is less stable than the powder and should be kept cold and used within a short working window. Choosing a solvent and storage conditions for your own work is your call, not ours.
Do I need bacteriostatic water to prepare it?
A lyophilised powder needs a solvent added before it can be worked with. Bacteriostatic water, which is water with 0.9% benzyl alcohol, is the common choice because the preservative extends the working life of the solution once the vial has been opened, and we supply it in 3ml and 10ml vials. It is not the only option: where a method cannot tolerate benzyl alcohol, use the solvent the method specifies. The choice affects the sample, so it belongs to the researcher.
How and when is an order shipped?
Orders are dispatched from the United Kingdom. An order placed before 4pm on a working day is collected the same day; weekends and bank holidays roll forward to the next working day. UK orders go by tracked DPD next-day delivery, free on orders over 14 pounds and 4.99 pounds below that. Tracking is sent when the parcel is collected, so the first scan is usually visible the same evening.
What is the ACTH(4-10) fragment, and why is it the basis of the design?
ACTH(4-10) is the central heptapeptide of adrenocorticotropic hormone, the portion of the parent hormone that has been studied in its own right in neuropeptide research. Building a compound from it is a deliberate reduction: the idea is to keep a short active sequence and drop the rest of the protein. The published work on such fragments is largely about structure and receptor interaction rather than about the parent hormone, and this page describes the chemistry only.
What does the proline-glycine-proline tail do?
It is there for stability. Peptidases work along a chain from one end, and a run of proline residues interrupts that process because proline's ring constrains the backbone into a shape those enzymes handle poorly. Adding the tail therefore extends the working lifetime of the molecule rather than adding a new activity. The tail is also largely responsible for the compound's retention behaviour on a reversed-phase column, since it makes the chain appreciably less polar than the core sequence alone.
Where is the oxidation risk?
At the N-terminal methionine. Methionine oxidises readily, and the product of that oxidation is sixteen daltons heavier than the starting material, which shifts the mass and typically moves the peak earlier on a reversed-phase run. It is a common modification to see on a purity trace and is not the same as a synthesis failure; it indicates how the material has been stored and handled. Limiting exposure to oxygen and to strongly oxidising conditions is the practical mitigation.
Why is a seven-residue peptide useful as a model compound?
It is short enough to be characterised unambiguously and modified in a controlled way, which makes it a convenient system for asking how a specific structural change affects stability or retention. That is a statement about its usefulness in method development and assay work, not about any application - the material is supplied for in-vitro laboratory research only.
What handling keeps the methionine intact?
Keeping the powder cold, dry, dark and sealed is the main measure, because oxidation needs oxygen and moisture. Once the material is in solution the risk rises sharply, since the peptide is then fully exposed to dissolved oxygen, so a working solution is best prepared when it is needed rather than held. Where a vial has been open for some time, checking the mass figure against the expected value is a quick way to see whether oxidation has occurred.
Is this compound found in nature?
No. It is synthetic, assembled from a fragment of a larger hormone with a stabilising tail added, and there is no naturally occurring peptide with this exact sequence to compare against. That matters for identity work: because there is no natural reference material, the certificate and the stated sequence are the definition of what the material is, rather than a comparison against something isolated from a biological source.
Documentation & batch verification
The current released lot is IP-SEMAX-5-001, tested 2026-08-24 by Janoshik Analytical (CZ): RP-HPLC purity 99.282% (RP-HPLC), measured content 5.68 mg/vial, identity Purity confirmed (RP-HPLC). The full report for this lot is published and can be checked online — verify this batch. See the full record for lot IP-SEMAX-5-001 or all published certificates of analysis.
Published batch records show the laboratory, report date, purity and measured content where reported. Check the certificate for the exact lot: an HPLC purity result does not establish LC-MS identity, sterility or suitability for human or animal use. Review the published batch record before ordering.
Order Semax 5mg online — UK dispatch · Request an invoice · Verify a batch
Research use only. Not for human or animal consumption.