KPV 10mg
£19.99 per vial · Peptides · Research use only
Available to order. Dispatch delayed while we await restock. We will email you with an update; a dispatch date is not yet confirmed. If you would rather not wait, reply to your confirmation email to cancel before dispatch for a full refund.
About KPV 10mg
KPV 10mg is a synthetic tripeptide composed of lysine, proline and valine, supplied as lyophilised powder in a single vial for in-vitro laboratory research.
Product specifications
- Compound
- KPV
- Declared content
- 10mg per vial
- Format
- Lyophilised powder
Batch documentation
The current published lot is IP-KPV10-001. The batch record from Janoshik Analytical (CZ), dated 24 August 2026, lists reported purity of 99.122% (RP-HPLC) and measured content of 12.76 mg/vial.
View the certificate of analysis →
Intended use
For in-vitro laboratory research only. Not for human or veterinary use.
Technical notes and further reading
- CAS number
- 67727-97-3
- Molecular formula
- C16H30N4O4
- Molecular weight
- 342.4 g/mol
- Sequence
- Lys-Pro-Val
Specification
| SKU | KPV10 |
|---|---|
| Compound | KPV |
| Price | £19.99 per vial |
| Format | 10mg per vial |
| Availability | Backorder — dispatch delayed |
| CAS number | 67727-97-3 |
| Molecular formula | C16H30N4O4 |
| Molecular weight | 342.4 g/mol |
| Sequence | Lys-Pro-Val |
| Published batch / lot | IP-KPV10-001 |
| Reported purity | 99.122% (RP-HPLC) |
| Measured content | 12.76 mg/vial |
| Identity status | LC-MS identity result not published |
| Tested by | Janoshik Analytical (CZ) |
| Report date | 2026-08-24 |
| Storage | Lyophilised: −20 °C, protect from light |
| Certificate of analysis | Published for lot IP-KPV10-001 — download it from this page, or request a copy |
| Intended use | In-vitro laboratory research only |
KPV 10mg research peptide: UK ordering
This KPV listing supplies 10mg of the single research compound per vial. Check the vial label and batch certificate when comparing it with blends containing KPV: a blend's total milligrams are not the quantity of each component. The price and current availability are shown on this page. Supplied from the UK for in-vitro laboratory research.
What does the research on KPV investigate?
KPV is a three-residue peptide - lysine, proline, valine - corresponding to the C-terminal end of alpha-melanocyte-stimulating hormone, and at 342.4 g/mol it sits at the boundary where a peptide is really a small organic molecule. That has practical consequences. Mass confirmation is unambiguous at this size, and the sequence is short enough to be assembled in high yield, so a batch is unlikely to carry the truncated sequences that complicate longer peptides. The difficulty is elsewhere: the lysine makes the molecule basic and the chain is very polar, so it retains poorly on a reversed-phase column and needs a method suited to a hydrophilic, charged species. Purity analysis for something this small also has to distinguish the target from closely related small molecules rather than from peptide by-products. The published literature studies the sequence as a fragment of alpha-MSH in cell models. This page describes the material and its documentation only.
Who can buy KPV?
KPV is supplied strictly as a research chemical for in-vitro laboratory research. Products are sold exclusively to qualified researchers and licensed laboratories.
At checkout the buyer confirms that they are 18 or over, are buying in the course of research, and are responsible for handling, storing and disposing of the material in line with their laboratory's procedures. KPV is not for human or veterinary use.
We only answer questions about specifications, documentation and orders.
How are identity and quality assured?
Each released lot is tested and the result is published, rather than the material being described as high purity on the strength of a supplier's word. Purity is measured by reversed-phase HPLC at an independent laboratory. The laboratory used for every lot published so far is Janoshik Analytical, in the Czech Republic, and the result is stated alongside the measured content against label so the two can be read together.
The report carries the lot number printed on the vial, which is the part that matters. A certificate showing a result without a lot number cannot be tied to the vial in front of you, and a certificate for a different lot tells you nothing about yours. Matching the printed number on the label to the number on the report is a five second check and it is the whole point of publishing both.
Identity confirmation by mass spectrometry is a separate test and is ordered as an add-on, so the figures published here come from RP-HPLC purity testing unless a report says otherwise. Where no report is published for a listing yet, the documentation held for the lot being shipped can be requested before you order. We would rather send you what exists than let you assume a certificate is available when it is not.
Synthesis and supply
Peptide material is built by solid-phase synthesis, purified by preparative HPLC, then lyophilised. Lyophilisation freezes the solution and removes the solvent under vacuum, which is why the vial arrives holding a cake or powder rather than a liquid and why a solvent has to be added before the material can be worked with. Removing water also removes the main route by which a peptide degrades in storage, which is the reason the format is used.
Sequence length and modification are what make batches differ in difficulty. Every coupling step is an opportunity for a truncated or deleted by-product, and a heavily modified or long chain presents more of them, which is why the purity trace rather than the headline figure is what a certificate is read for. Vials are filled and labelled with the lot number, and the lot number is what the report and the verification lookup resolve against.
External resources for researchers
These are the public reference sources we use when checking the identity of KPV, and the ones worth going to before relying on anything stated on a product page, including this one.
- PubChem — Compound records, computed properties, depositor-supplied identity data.
- CAS Common Chemistry — CAS Registry lookups where a registry number is known.
- ChEBI — Curated chemical ontology entries with cross-references.
- Europe PMC — Primary literature search by compound name, sequence or registry number.
- Certificate hub — Reports published for the lots released so far.
Frequently asked questions
Where does the KPV sequence come from?
It corresponds to residues 11 to 13 of alpha-melanocyte-stimulating hormone — the last three of that thirteen-residue chain. The tripeptide is studied on its own account rather than as a degradation product, and it carries its own registry identity, CAS 67727-97-3.
How does its molar content compare with the larger peptides here?
Very favourably. At 342.4 g/mol, 10mg is roughly 30 micromoles; the same 10mg of a 4.7 kDa peptide is closer to 2 micromoles. Any calculation expressed in molar terms should be built from the molecular weight rather than from the label mass.
Does KPV bind melanocortin receptors the way the full analogues do?
It lacks the core message sequence that gives the full alpha-MSH analogues their receptor affinity, and the in-vitro literature generally handles it as a distinct entity rather than as a short melanocortin agonist. Index Peptides supplies the tripeptide as a research material and offers no view on mechanism.
Is KPV supplied for human or veterinary use?
No. KPV is supplied as a lyophilised powder in a sealed vial and is supplied strictly as a research chemical for in-vitro laboratory research. Products are sold exclusively to qualified researchers and licensed laboratories, and buyers confirm they are 18 or over and purchasing in the course of research. We only answer questions about specifications, documentation and orders.
How is the purity figure measured, and what does it actually tell me?
Purity is measured by reversed-phase HPLC at an independent laboratory, and the result is published with the method conditions rather than as a bare percentage. The figure is the proportion of the UV-absorbing material in the chromatogram that elutes as the target peak. It describes the sample as analysed; it is not a statement about what the material is for. A high figure alongside a clean chromatogram is the useful combination, which is why the report is worth reading rather than the headline number alone.
What documentation comes with a batch?
Each released lot carries a number printed on the vial label and a report stating purity by RP-HPLC, measured content against label, and the testing laboratory. Reports published so far are listed on this page and collected on the certificate hub, and each carries a lot number that can be checked against the vial in front of you. Where a report is not yet published for a listing, ask before ordering and we will send the documentation that exists for the lot being shipped.
How should KPV be stored?
In the form supplied, as a lyophilised powder, the material is stable kept cold, dry and dark. For powder, that means a freezer at around minus 20 degrees Celsius, desiccated, with the vial sealed and shielded from light, which is how it should stay until you are ready to work with it. Bringing a vial to room temperature before opening avoids condensation on the contents. Once in solution the material is less stable than the powder and should be kept cold and used within a short working window. Choosing a solvent and storage conditions for your own work is your call, not ours.
Do I need bacteriostatic water to prepare it?
A lyophilised powder needs a solvent added before it can be worked with. Bacteriostatic water, which is water with 0.9% benzyl alcohol, is the common choice because the preservative extends the working life of the solution once the vial has been opened, and we supply it in 3ml and 10ml vials. It is not the only option: where a method cannot tolerate benzyl alcohol, use the solvent the method specifies. The choice affects the sample, so it belongs to the researcher.
How and when is an order shipped?
Orders are dispatched from the United Kingdom. An order placed before 4pm on a working day is collected the same day; weekends and bank holidays roll forward to the next working day. Delivery is tracked, and shipping is free on UK orders over 30 pounds, with tracked 48 hour service at 3.65 pounds below that. Tracking is sent when the parcel is collected, so the first scan is usually visible the same evening.
What is the relationship between KPV and alpha-MSH?
KPV corresponds to the final three residues of alpha-melanocyte-stimulating hormone, a much larger peptide hormone. It is the smallest fragment of that hormone to have been studied in its own right in the published literature, which is the reason a tripeptide attracts any research interest at all. The relationship is structural: the fragment is a distinct molecule with its own mass and behaviour, not a shorthand for the parent hormone.
Why is KPV awkward to analyse by HPLC?
Because it has almost nothing for a reversed-phase column to hold on to. Retention in that mode depends on hydrophobic character, and a chain of lysine, proline and valine is dominated by a charged, polar residue. The result is a very short retention time, often close to the solvent front, where resolution from other polar material is poor. Ion pairing or a different separation mode is usually the answer rather than a longer gradient.
At this molecular weight, is it still a peptide?
Chemically it is a peptide because the residues are joined by peptide bonds, but at 342.4 g/mol it behaves more like a small organic molecule in several respects. Its mass is low enough that a single structural difference is a large fractional change, and its physical properties - solubility, volatility, retention - are those of a small polar compound. That affects which analytical techniques are appropriate rather than what the substance is.
How should the powder be handled?
As with any lyophilised material: cold, dry and dark until needed, and allowed to reach room temperature before the vial is opened so that condensation does not form on the contents. The sequence contains no cysteine, methionine or tryptophan, so there is no specific oxidative liability, and a three-residue chain has little to degrade. Once in solution it is less stable than the powder.
Documentation & batch verification
The current released lot is IP-KPV10-001, tested 2026-08-24 by Janoshik Analytical (CZ): RP-HPLC purity 99.122% (RP-HPLC), measured content 12.76 mg/vial, identity Purity confirmed (RP-HPLC). The full report for this lot is published and can be checked online — verify this batch. See the full record for lot IP-KPV10-001 or all published certificates of analysis.
Published batch records show the laboratory, report date, purity and measured content where reported. Check the certificate for the exact lot: an HPLC purity result does not establish LC-MS identity, sterility or suitability for human or animal use. Review the published batch record before ordering.
Order KPV 10mg online — UK dispatch · Request an invoice · Verify a batch
Research use only. Not for human or animal consumption.