KPV 10mg
£19.99 per vial · Healing & repair · Research use only
KPV 10mg research peptide — a synthetic tripeptide of L-lysine, L-proline and L-valine (the C-terminal fragment of alpha-melanocyte-stimulating hormone, CAS 67727-97-3), supplied lyophilised for in-vitro laboratory research. HPLC purity and LC-MS identity verified per batch, with the COA available on request. UK dispatch.
KPV in research
Three residues — lysine, proline, valine — make KPV the shortest sequence in the catalogue and, at 327.4 g/mol under CAS 67727-97-3, the lightest peptide listed. The sequence is not arbitrary: it is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone, positions 11 to 13 of that hormone, which is why it appears in melanocortin literature despite carrying none of the receptor-binding core of the full analogues. Most of its in-vitro citations sit in cell-culture work on inflammatory signalling pathways. Ten milligrams of a molecule this light is around 30 micromoles. Sequences this short are also comparatively straightforward to assemble cleanly, so the analytical questions on a lot tend to concern identity and counterion rather than deletion sequences.
Specification
| Compound | KPV |
|---|---|
| CAS number | 67727-97-3 |
| Molecular formula | C16H29N3O4 |
| Molecular weight | 327.4 g/mol |
| Sequence | Lys-Pro-Val |
| Vial size | 10mg per vial |
| Physical form | Lyophilised powder |
| Research class | Healing & repair |
| Purity method | RP-HPLC |
| Identity method | LC-MS |
| Documentation | Certificate of analysis available on request |
| Intended use | In-vitro laboratory research only |
Frequently asked questions
Where does the KPV sequence come from?
It corresponds to residues 11 to 13 of alpha-melanocyte-stimulating hormone — the last three of that thirteen-residue chain. The tripeptide is studied on its own account rather than as a degradation product, and it carries its own registry identity, CAS 67727-97-3.
How does its molar content compare with the larger peptides here?
Very favourably. At 327.4 g/mol, 10mg is roughly 30 micromoles; the same 10mg of a 4.7 kDa peptide is closer to 2 micromoles. Any calculation expressed in molar terms should be built from the molecular weight rather than from the label mass.
Does KPV bind melanocortin receptors the way the full analogues do?
It lacks the core message sequence that gives the full alpha-MSH analogues their receptor affinity, and the in-vitro literature generally handles it as a distinct entity rather than as a short melanocortin agonist. Index Peptides supplies the tripeptide as a research material and offers no view on mechanism.
Documentation & batch verification
KPV is analysed per batch: RP-HPLC for purity and LC-MS for identity, with the certificate of analysis available on request. Each released lot number is checkable on our batch verification page, and our documentation standards set out exactly what is reviewed before a product is listed.
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Research use only. Not for human or animal consumption.