GLP-3 (RT) — Compound Overview
A researcher-focused overview of GLP-3 (RT): its chemistry as an engineered incretin-receptor peptide, its supply status, and how each batch is documented.
Last updated: 2026-08-21 · By: Index Peptides technical team
Key facts about GLP-3 (RT)
| Compound | GLP-3 (RT) |
|---|---|
| CAS number | 2381089-83-2 |
| Molecular formula | C221H342N46O68 |
| Molecular weight | 4731.3 g/mol |
| Sequence | 39-residue modified peptide |
| Listed formats | 10mg per vial, 40mg per vial |
| Intended use | In-vitro laboratory research only |
What is GLP-3 (RT)?
GLP-3 (RT) is a synthetic 39-residue modified peptide engineered to act as an agonist at three receptors: the glucose-dependent insulinotropic polypeptide (GIP) receptor, the glucagon-like peptide-1 (GLP-1) receptor, and the glucagon receptor. It is built on a GIP-like backbone with non-natural amino-acid substitutions and a C20 fatty-diacid moiety attached via a linker (lipidation).
Chemistry and structure
GLP-3 (RT) carries CAS registry number 2381089-83-2, molecular formula C221H342N46O68 and a molecular weight of approximately 4731.3 g/mol, making it one of the largest peptides in this catalogue. Its size and lipidation make manufacturing and analytical characterisation more demanding, which is reflected in batch-level documentation.
Supply status
Index Peptides supplies GLP-3 (RT) strictly as a research chemical for in-vitro laboratory research. Products are sold exclusively to qualified researchers and licensed laboratories. It is not for human or veterinary use.
This compound in the research literature
The compound appears in the incretin-receptor pharmacology literature as a multi-receptor agonist tool compound used in receptor-binding and signalling assays. Index Peptides lists it as a technical research material only and takes no position on any application.
Form, handling and storage
Supplied as a lyophilised powder in a sealed vial. Store at -20°C, desiccated and protected from light, per the batch record. Lipidated peptides can show different solubility behaviour from unmodified peptides; reconstitution conditions are part of the experimental design and are not advised by Index Peptides.
Batch documentation at Index Peptides
Review the published certificate for the exact lot, including the laboratory, report date and analytical results actually reported. HPLC purity alone does not confirm LC-MS identity. Contact us before ordering if a required result is not published.
Frequently asked questions
Who is GLP-3 (RT) supplied to?
Index Peptides supplies GLP-3 (RT) exclusively to qualified researchers and licensed laboratories, for in-vitro research only. It is not for human or veterinary use.
Why is identity testing especially important for GLP-3 (RT)?
At ~4.7 kDa with non-natural residues and a fatty-diacid modification, GLP-3 (RT) is difficult to synthesise correctly. LC-MS identity confirmation (expected vs detected mass) on the COA is the check that the vial contains the right molecule.
Why is it invoice-only rather than direct checkout?
GLP-3 (RT) is held to stricter payment and listing review. Orders go through the invoice flow.
What is the shelf life of GLP-3 (RT)?
As supplied (lyophilised powder in a sealed vial), GLP-3 (RT) is stored at -20C, desiccated and protected from light. Long-term stability is documented per batch on the certificate of analysis; treat the batch record as the authoritative shelf-life reference for that lot.
What is the difference between the sizes?
The difference is the nominal peptide content per vial. GLP-3 (RT) is supplied as the formats listed on the product page. Every format carries the same batch documentation and purity testing.
What does the certificate of analysis show?
Review the published certificate for the exact lot, including the laboratory, report date and analytical results actually reported. HPLC purity alone does not confirm LC-MS identity. Contact us before ordering if a required result is not published.
References
Research use only. Not for human or animal consumption.